Head west from Laramie on state Highway 130, which becomes the Snowy Range Scenic Byway across the Medicine Bow Mountains. This road, which tops out near 11,000 feet features plenty of fall color and thrilling views of mountaintop vistas and alpine lakes.

Southwest of the byway, state Highway 70 leads west out of Encampment to a stretch known whose showy autumn displays have earned it the name Aspen Alley. Spend the night in historic comfort at either the Wolf Hotel in Saratoga (a short walk from the town's famous hot springs) or the Elk Mountain Hotel.